FatigueBlock (Sodio Bicarbonato Enterico) - 120 Capsule

Pubblicazione 1993 — abstract non disponibile: non vengono dedotti risultati.

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Studio randomizzato. Introduction Objective: to investigate the impact and safety of Chinese Modified Dietary Approaches to Stop Hypertension (CM-DASH) combined with sodium-restricted formula salts on home blood pressure monitoring (HBPM) in patients with hypertension and type 2 diabetes. Material and methods: employing a semi-open randomized, controlled, single-blind trial, patients were allocated into four groups-Group A (control), Group B (52 % salt), Group C (23 % salt), and Group D (meal packs)-for an eight-week dietary intervention. Throughout the intervention, patients self-measured their blood pressure daily and were followed up weekly. Additionally, 24-hour urine was performed at baseline, week 4, and the end of the intervention. Results: of the 132 initial participants, only two were lost to follow-up. Following an 8-week intervention, blood pressure exhibited a downward trend across all four subject groups (p < 0.05). Both HS

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Revisione. Esta hoja trata sobre la exposición al docusato de sodio en el embarazo y durante la lactancia. Esta información se basa en la literatura publicada disponible. No debe usarse como un sustituto de la atención médica o los consejos de su proveedor de atención de salud.

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Revisione. Introduction Excess salt intake is one of the relevant dietary determinants of elevated blood pressure and hypertension, with a direct impact on cardiovascular risk. In today's food environment, a substantial proportion of sodium comes from "hidden salt" added to processed and ultra-processed foods, which limits the effectiveness of interventions focused exclusively on the salt shaker and reinforces the need for combined strategies. The most robust scientific evidence shows that reducing sodium/salt lowers blood pressure, with a greater effect in people with hypertension and in salt-sensitive profiles. Although associations have been reported with other outcomes, such as gastric cancer, kidney stones and bone mineral balance, or cognitive decline, study findings are more heterogeneous and require cautious interpretation. Part of the current controversy arises from observational results suggesting non-linear associations and a

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Revisione. Chronic kidney disease, diabetes mellitus and heart failure represent three chronic conditions closely linked to each other from a pathophysiological and prognostic point of view. This link has led to an ever-increasing emphasis in recent years on the need for a holistic approach to patients who are affected by optimizing the therapeutic management of what has recently been defined as cardio-kidney-metabolic syndrome. The cardiorenal and metabolic approach has gained relevance thanks to recent studies on new drug classes. Initially in diabetic patients and later in those suffering from heart failure and chronic kidney disease, these new drugs have demonstrated their effectiveness in reducing cardiovascular risk, the progression of heart failure and chronic kidney disease. This review aims to address the main pharmacological aspects of two of these new classes, that of sodium-glucose co-transporter 2 inhibitors and the more re

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Studio randomizzato. Introduction Background and purpose: the Dietary Approaches to Stop Hypertension (DASH) diet has multifunctional health benefits. We evaluated the effects of low-sodium salt applied to Chinese modified DASH diet on arterial stiffness in older patients with hypertension and type 2 diabetes. Methods: sixty-one older adults with hypertension and type 2 diabetes were randomly allocated to low sodium salt group (n = 31) or normal sodium salt group (n = 30). They were given the Chinese modified DASH diet plus low-sodium salt (52 % sodium chloride) or same diet plus regular salt (99 % sodium chloride) for eight weeks, respectively. Brachial and ankle pulse wave conduction velocity, ankle brachial index and atherosclerosis-related indices were measured at baseline and week 8. In addition, 24-hour urine and blood samples were measured at baseline, the 4th week and the end of the intervention. Results: as compared with the ba

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Revisione. Diabetic cardiomyopathy (DCM) is a complication of type 2 diabetes mellitus (T2DM) capable of progressing to the development of symptomatic heart failure (HF), independently of traditional risk factors for it, such as coronary artery disease and hypertension. There is no specific treatment for DCM; however, sodium-glucose cotransporter 2 inhibitors (SGLT2i) are hypoglycemic drugs that act on SGLT2 channels, inhibiting glucose reabsorption in the kidney. In addition, they have cardioprotective effects, which is why their mechanisms at the cardiac level have been studied. According to the results of preclinical studies, SGLT2i act by interfering in the pathophysiology of DCM. Their main effects are: improvement in diastolic function and left ventricular ejection fraction (LVEF), attenuation in the progress of cardiac fibrosis, reduction of oxidative stress and proinflammatory markers. The clinical trials in humans specifically

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